Basic Information
| LncRNA/CircRNA Name | circ_0084043 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | melanoma |
| ICD-0-3 | NA |
| Methods | qPCR, western blot, flow cytometry and transwell assays |
| Sample | melanoma tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Expression of circ_0084043 and TRIB2 was upregulated in human melanoma tissues and cell lines. Both circ_0084043 knockdown and TRIB2 silencing could decrease cell proliferation, migration and invasion, but facilitate apoptosis in A375 and SK-MEL-28 cells. |
| Pubmed ID | 31954160 |
| Year | 2020 |
| Title | Knockdown of circ_0084043 suppresses the development of human melanoma cells through miR-429/tribbles homolog 2 axis and Wnt/?-catenin pathway |
External Links
| Links for circ_0084043 | GenBank HGNC NONCODE |
| Links for melanoma | OMIM COSMIC |