Basic Information
| LncRNA/CircRNA Name | circ_0004277 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR |
| Sample | colorectal cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | High circ-0004277 expression was then verified in tissue samples and cell lines of colorectal cancer via qRT-PCR. Kaplan-Meier analysis was used for identifying the association between circ-0004277 expression and the overall survival rate of colorectal cancer patients. circ-0004277 knockdown accelerated cell apoptosis and restrained cell proliferation of colorectal cancer. |
| Pubmed ID | 31960446 |
| Year | 2020 |
| Title | Circular RNA hsa_circ_0004277 contributes to malignant phenotype of colorectal cancer by sponging miR-512-5p to upregulate the expression of PTMA |
External Links
| Links for circ_0004277 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |