Basic Information
| LncRNA/CircRNA Name | circBACH1 |
| Synonyms | circ_0061395 |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, RNA immunoprecipitation assays, pull-down assays, and electrophoretic mobility shift assays |
| Sample | liver cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | Here, we found that circBACH1 was significantly upregulated in HCC tissues and that high circBACH1 levels were closely associated with poor prognosis. In addition, circBACH1 could promote HCC growth by accelerating cell cycle progression in vitro and in vivo. |
| Pubmed ID | 32003018 |
| Year | 2020 |
| Title | CircBACH1 (hsa_circ_0061395) promotes hepatocellular carcinoma growth by regulating p27 repression via HuR |
External Links
| Links for circBACH1 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |