Basic Information
| LncRNA/CircRNA Name | circMAN2B2 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, CCK-8 assay, colony formation assay, flow cytometer, Transwell assay, and Western blot |
| Sample | gastric cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | circMAN2B2 was high-expressed in GC tissues. Silence of circMAN2B2 clearly declined SNU-16 and AGS cells viability, survival, migration but enhanced apoptosis. |
| Pubmed ID | 32020674 |
| Year | 2020 |
| Title | Circular RNA circMAN2B2 promotes growth and migration of gastric cancer cells by down-regulation of miR-145 |
External Links
| Links for circMAN2B2 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |