Basic Information
| LncRNA/CircRNA Name | circMORC3 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hypopharyngeal cancer |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | hypopharyngeal cancer tissues, plasma |
| Expression Pattern | down-regulated |
| Function Description | The expression levels of circMORC3 were significantly lower in HSCC tissues than paired adjacent normal tissues. The decreased expression of circMORC3 was correlated to T stages and tumor sizes. Similarly, the circMORC3 expression levels in HSCC patient plasma were lower than non-tumor patient plasma. |
| Pubmed ID | 32021421 |
| Year | 2020 |
| Title | Diagnostic Significance of Downregulated circMORC3 as a Molecular Biomarker of Hypopharyngeal Squamous Cell Carcinoma: A Pilot Study |
External Links
| Links for circMORC3 | GenBank HGNC NONCODE |
| Links for hypopharyngeal cancer | OMIM COSMIC |