Basic Information
| LncRNA/CircRNA Name | circ_0007874 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR, luciferase reporter assay |
| Sample | ovarian cancer cell lines |
| Expression Pattern | down-regulated |
| Function Description | Results verified that hsa_circ_0007874 is downregulated in OVA cell lines. hsa_circ_0007874 overexpression decreased the OVA cell migration and proliferation in vitro and in vivo. |
| Pubmed ID | 32023009 |
| Year | 2020 |
| Title | Upregulation of hsa_circ_0007874 suppresses the progression of ovarian cancer by regulating the miR-760/SOCS3 pathway |
External Links
| Links for circ_0007874 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |