Basic Information
| LncRNA/CircRNA Name | circCEP85L |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Cell Counting Kit-8, wound healing, Transwell, and tumorsphere formation assays |
| Sample | gastric cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | We found that circ-CEP85L, which has not been studied in GC, was significantly downregulated in GC tissues and that decreased circ-CEP85L expression correlated significantly with a worse prognosis. The knockdown of circ-CEP85L promoted the proliferation and invasion of GC cells, which was reversed by overexpression of circ-CEP85L. |
| Pubmed ID | 32026471 |
| Year | 2020 |
| Title | circ-CEP85L suppresses the proliferation and invasion of gastric cancer by regulating NFKBIA expression via miR-942-5p |
External Links
| Links for circCEP85L | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |