Basic Information
LncRNA/CircRNA Name | circ_0000092 |
Synonyms | |
Region | |
Ensemble | |
Refseq |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | liver cancer |
ICD-0-3 | C22.0 |
Methods | qPCR, Dual luciferase reporter, RNA pull-down and northern blot assays |
Sample | liver cancer tissues and cell lines |
Expression Pattern | up-regulated |
Function Description | Moreover, depleted hsa_circ_0000092 or elevated miR-338-3p was shown to suppress HCC cell proliferation, migration, invasion and angiogenesis in vitro via down-regulation of HN1. |
Pubmed ID | 32077624 |
Year | 2020 |
Title | hsa_circ_0000092 promotes hepatocellular carcinoma progression through up-regulating HN1 expression by binding to microRNA-338-3p |
External Links
Links for circ_0000092 | GenBank HGNC NONCODE |
Links for liver cancer | OMIM COSMIC |