Basic Information
| LncRNA/CircRNA Name | circ_0058124 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | thyroid cancer |
| ICD-0-3 | C73.9 |
| Methods | qPCR, western blotting, Dual luciferase reporter, RNA immunoprecipitation (RIP) and RNA pull-down assays |
| Sample | thyroid cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | Circ_0058124 was highly expressed in TC and is a stable cyclic transcript, mainly located in the cytoplasm. Circ_0058124 knockdown suppressed proliferation, migration, invasion and metabolic abilities in TC cells. |
| Pubmed ID | 32110054 |
| Year | 2020 |
| Title | Circ_0058124 Upregulates MAPK1 Expression to Promote Proliferation, Metastasis and Metabolic Abilities in Thyroid Cancer Through Sponging miR-940 |
External Links
| Links for circ_0058124 | GenBank HGNC NONCODE |
| Links for thyroid cancer | OMIM COSMIC |