Basic Information
| LncRNA/CircRNA Name | circDDX17 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blotting |
| Sample | colorectal cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | CircDDX17 and KANK1 were down-regulated. CircDDX17 inhibited 5-Fu resistance and CRC progression via sponging miR-31-5p. |
| Pubmed ID | 32141542 |
| Year | 2020 |
| Title | CircDDX17 reduces 5-fluorouracil resistance and hinders tumorigenesis in colorectal cancer by regulating miR-31-5p/KANK1 axis |
External Links
| Links for circDDX17 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |