Basic Information
| LncRNA/CircRNA Name | circ_0088732 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, fluorescence?in situ?hybridization (FISH), Sanger sequencing, and PCR assays |
| Sample | glioma tissues |
| Expression Pattern | up-regulated |
| Function Description | We verified that hsa_circ_0088732 is circular and highly expressed in glioma tissues. Knockdown of hsa_circ_0088732 induced glioma cell apoptosis and inhibited glioma cell migration, invasion, and epithelial-mesenchymal transition (EMT). |
| Pubmed ID | 32154171 |
| Year | 2020 |
| Title | Lcn2-derived Circular RNA (hsa_circ_0088732) Inhibits Cell Apoptosis and Promotes EMT in Glioma via the miR-661/RAB3D Axis |
External Links
| Links for circ_0088732 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |