Basic Information
| LncRNA/CircRNA Name | circPIP5K1A |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, colony formation, transwell and western blot assays |
| Sample | gastric cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | CircPIP5K1A was up-regulated in GC tissues and cells with a circular structure. Functionally, circPIP5K1A silence limited cell proliferation, invasion, migration and EMT process. Mechanistically, circPIP5K1A directly interacted with miR-671-5p to modulate KRT80 expression. |
| Pubmed ID | 32169757 |
| Year | 2020 |
| Title | CircPIP5K1A activates KRT80 and PI3K/AKT pathway to promote gastric cancer development through sponging miR-671-5p |
External Links
| Links for circPIP5K1A | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |