Basic Information
LncRNA/CircRNA Name | circ_0058063 |
Synonyms | |
Region | |
Ensemble | |
Refseq |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | bladder cancer |
ICD-0-3 | C67 |
Methods | qPCR, Luciferase reporter assays and RIP |
Sample | bladder cancer tissues and cell lines |
Expression Pattern | up-regulated |
Function Description | circRNA_0058063 was overexpressed in BC tissues compared with adjacent normal tissues. Knockdown of circRNA_0058063 dramatically decreased cell proliferation and invasion, and promoted apoptosis in 5637 and BIU-87 cell lines. |
Pubmed ID | 32181485 |
Year | 2020 |
Title | CircRNA_0058063 functions as a ceRNA in bladder cancer progression via targeting miR-486-3p/FOXP4 axis |
External Links
Links for circ_0058063 | GenBank HGNC NONCODE |
Links for bladder cancer | OMIM COSMIC |