Basic Information
| LncRNA/CircRNA Name | circFOXM1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, RNA immunoprecipitation, luciferase analysis, RNA pull-down, and rescue assay |
| Sample | non-small cell lung cancer tissues |
| Expression Pattern | up-regulated |
| Function Description | We found that circFOXM1 was significantly upregulated in NSCLC tissues, and its upregulation was positively correlated with advanced clinical stage and poor prognosis of NSCLC patients. Gain or loss-of-function assay showed that circFOXM1 promoted cell proliferation and cell cycle progression. |
| Pubmed ID | 32228656 |
| Year | 2020 |
| Title | circFOXM1 promotes proliferation of non-small cell lung carcinoma cells by acting as a ceRNA to upregulate FAM83D |
External Links
| Links for circFOXM1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |