Basic Information
| LncRNA/CircRNA Name | circMAN2B2 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | liver cancer |
| ICD-0-3 | C22.0 |
| Methods | qPCR, knockdown |
| Sample | liver cancer tissue |
| Expression Pattern | differential expressed |
| Function Description | We found that knockdown of circMAN2B2 expression in the HCC cell lines Hep-G2 and Huh-7 significantly inhibited cell proliferation by sponging (miRNA) miR-217 and inhibiting its function. |
| Pubmed ID | 32231737 |
| Year | 2020 |
| Title | Circular RNA MAN2B2 promotes cell proliferation of hepatocellular carcinoma cells via the miRNA-217/MAPK1 axis |
External Links
| Links for circMAN2B2 | GenBank HGNC NONCODE |
| Links for liver cancer | OMIM COSMIC |