Basic Information
| LncRNA/CircRNA Name | circFNDC3B |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | qPCR, CCK8 assays, colony formation assays, transwell assays, wound-healing assays |
| Sample | colon cancer tissues and cell lines |
| Expression Pattern | down-regulated |
| Function Description | The patients with low circFNDC3B expression had a shorter OS (P????.0014) than patients with high expression. Moreover, circFNDC3B inhibited the proliferation, invasion and migration of CC cells. Furthermore, circFNDC3B-218aa, not circFNDC3B, inhibited the proliferation, invasion and migration of CC. |
| Pubmed ID | 32241279 |
| Year | 2020 |
| Title | A novel protein encoded by circFNDC3B inhibits tumor progression and EMT through regulating Snail in colon cancer |
External Links
| Links for circFNDC3B | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |