Basic Information
| LncRNA/CircRNA Name | circSCARB1 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | renal cancer |
| ICD-0-3 | C64.9 |
| Methods | qPCR, flow cytometry, western blotting |
| Sample | renal cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | Circ-SCARB1 was elevated in 30 pairs of RCC tissues and multiple RCC cell lines. Knockdown of Circ-SCARB1 inhibited cell proliferation, migration and invasion, while inducing cell apoptosis. |
| Pubmed ID | 32271695 |
| Year | 2020 |
| Title | CircRNA SCARB1 promotes renal cell carcinoma progression via miR-510-5p/SDC3 axis |
External Links
| Links for circSCARB1 | GenBank HGNC NONCODE |
| Links for renal cancer | OMIM COSMIC |