Basic Information
| LncRNA/CircRNA Name | circ_0002052 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR |
| Sample | osteosarcoma tissues |
| Expression Pattern | up-regulated |
| Function Description | Up-regulated circ-0002052 was associated with advanced stage, tumor size, and metastasis. Additionally, circ-0002052 elevation indicated a low survival rate in OS patients and silencing of circ-0002052 suppressed proliferation, migration, and invasion of OS cells. It was proved that circ-0002052 sponged miR-382 and stimulated STX6 expression |
| Pubmed ID | 32274658 |
| Year | 2020 |
| Title | Circular RNA hsa_circ_0002052 promotes osteosarcoma via modulating miR-382/STX6 axis |
External Links
| Links for circ_0002052 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |