Basic Information
| LncRNA/CircRNA Name | circBIRC6 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR, RIP |
| Sample | non-small cell lung cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | We found that circBIRC6 was upregulated in primary human NSCLC tissues and NSCLC cells, whereas its potential target, miR-145, was downregulated. shRNA-induced silencing of circBIRC6 potently inhibited their growth, proliferation, migration and invasion. |
| Pubmed ID | 32297303 |
| Year | 2020 |
| Title | CircRNA BIRC6 promotes non-small cell lung cancer cell progression by sponging microRNA-145 |
External Links
| Links for circBIRC6 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |