Basic Information
| LncRNA/CircRNA Name | circFoxO3a |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | cervical cancer |
| ICD-0-3 | C53 |
| Methods | qPCR |
| Sample | cervical cancer tissue, serum |
| Expression Pattern | down-regulated |
| Function Description | Levels of serum circFoxO3a were decreased in SCC patients compared with controls. Low expression of circFoxO3a was correlated with deeper stromal invasion and positive lymph node metastasis. Moreover, SCC patients with lower expression of serum circFoxO3a showed poorer prognosis, including both overall survival (OS) and recurrence-free survival (RFS). |
| Pubmed ID | 32308490 |
| Year | 2020 |
| Title | Serum Circular FoxO3a Serves as a Novel Prognostic Biomarker in Squamous Cervical Cancer |
External Links
| Links for circFoxO3a | GenBank HGNC NONCODE |
| Links for cervical cancer | OMIM COSMIC |