Basic Information
| LncRNA/CircRNA Name | circ_001275 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal cancer |
| ICD-0-3 | C15 |
| Methods | qPCR, Western blotting |
| Sample | esophageal cancer tissues and cell lines |
| Expression Pattern | up-regulated |
| Function Description | The results showed that circRNA_001275 was significantly upregulated in cisplatin??esistant esophageal cancer tissues and cells (P<0.05). Overexpression of circRNA_001275 promoted the proliferation and invasion, and decreased the apoptosis of cisplatin??esistant cells. On the other hand, circRNA_001275 silencing inhibited cell proliferation and invasion, and promoted cell apoptosis (P<0.05). |
| Pubmed ID | 32319613 |
| Year | 2020 |
| Title | circRNA_001275 upregulates Wnt7a expression by competitively sponging miR??70??p to promote cisplatin resistance in esophageal cancer |
External Links
| Links for circ_001275 | GenBank HGNC NONCODE |
| Links for esophageal cancer | OMIM COSMIC |