Basic Information
| LncRNA/CircRNA Name | circ-0000745 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute lymphoblastic leukemia |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot etc. |
| Sample | human leukemia cell line (Kasumi-1 and KG-1 cells), human primary T lymphocytes Cells (T cell) |
| Expression Pattern | up-regulated |
| Function Description | Upregulated the expression of circ-0000745 significantly enhanced the proliferation of Kasumi-1 and KG-1 cells, and reduced the ratio of apoptosis cells. |
| Pubmed ID | 32360844 |
| Year | 2020 |
| Title | Upregulation of circ-0000745 in acute lymphoblastic leukemia enhanced cerll proliferation by activating ERK pathway |
External Links
| Links for circ-0000745 | GenBank HGNC NONCODE |
| Links for acute lymphoblastic leukemia | OMIM COSMIC |