Basic Information
| LncRNA/CircRNA Name | circ_0102272 |
| Synonyms | |
| Region | |
| Ensemble | |
| Refseq |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | thyroid cancer |
| ICD-0-3 | C73.9 |
| Methods | qPCR |
| Sample | thyroid cancer tissue, cell lines |
| Expression Pattern | up-regulated |
| Function Description | Both sequencing and RT-qPCR corroborated that hsa_circ_0102272 was dramatically elevated in TC tissues and cell lines compared with the control group. Patients with high expression of hsa_circ_0102272 showed significantly short overall survival and progression-free survival compared with those patients with hsa_circ_0102272 low expression. In vitro experiments validated that knockdown of hsa_circ_0102272 could restrain cell proliferation, migration and invasion, and facilitate apoptosis of TC cells in vitro. |
| Pubmed ID | 32367651 |
| Year | 2020 |
| Title | Hsa_circ_0102272 serves as a prognostic biomarker and regulates proliferation, migration and apoptosis in thyroid cancer |
External Links
| Links for circ_0102272 | GenBank HGNC NONCODE |
| Links for thyroid cancer | OMIM COSMIC |