Basic Information
| LncRNA/CircRNA Name | ZNRD1-AS1 |
| Synonyms | ZFAS1, C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1-AS1 |
| Region | GRCh38_20:49278178-49295738 |
| Ensemble | ENSG00000177410 |
| Refseq | NR_003604 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | endometrial cancer |
| ICD-0-3 | NA |
| Methods | qRT-PCR etc. |
| Sample | EC tissues and corresponding normal tissues ,Ishikawa cells |
| Expression Pattern | up-regulated |
| Function Description | Higher expression of ZNRD1-AS1 and lower expression of ZNRD1 were detected in the EC tissues, compared to the normal tissues.Minor allele of rs9261204 was significantly associated with increased risk of EC. Furthermore, Ishikawa cells with rs9261204 G allele had lower mRNA level of ZNRD1, compared to the A allele. |
| Pubmed ID | 31599404 |
| Year | 2019 |
| Title | A Functional Cis-eQTL Locus in lncRNA ZNRD1-AS1 Contributes to the Susceptibility of Endometrial Cancer |
External Links
| Links for ZNRD1-AS1 | GenBank HGNC NONCODE |
| Links for endometrial cancer | OMIM COSMIC |