Basic Information
| LncRNA/CircRNA Name | lncRNA-ZNF281 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | HCC tissues,cell lines |
| Expression Pattern | up-regulated |
| Function Description | ZNF281 overexpression led to enhanced and miR-539 overexpression led to suppressed HCC cell invasion and migration. In addition, miR-539 overexpression attenuated the effects of ZNF281 overexpression. ZNF281 may interact with miR-539 to promote HCC cell invasion and migration. |
| Pubmed ID | 32073896 |
| Year | 2020 |
| Title | LncRNA-ZNF281 Interacts with miR-539 to Promote Hepatocellular Carcinoma Cell Invasion and Migration |
External Links
| Links for lncRNA-ZNF281 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |