Basic Information
| LncRNA/CircRNA Name | ZMAT1 |
| Synonyms | ZMAT1 |
| Region | GRCh38_X:101882288-101932031 |
| Ensemble | ENSG00000166432 |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR etc. |
| Sample | gastric cancer tissues |
| Expression Pattern | down-regulated |
| Function Description | We found for the first time that the lncRNA ZMAT1 transcript variant 2 is downregulated in gastric cancer tissues compared with adjacent normal tissues. The expression of ZMAT1 transcript variant 2 was inversely correlated with lymph node metastasis, depth of tumor invasion and tumor node metastasis stage. Univariate and multivariate analyses showed that ZMAT1 transcript variant 2 expression was an independent predictor for overall survival |
| Pubmed ID | 26191264 |
| Year | 2015 |
| Title | Downregulation of long noncoding RNA ZMAT1 transcript variant 2 predicts a poor prognosis in patients with gastric cancer |
External Links
| Links for ZMAT1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |