Basic Information
| LncRNA/CircRNA Name | CASC9 |
| Synonyms | NA |
| Region | GRCh38_8:75223404-75324741 |
| Ensemble | ENSG00000249395 |
| Refseq | NR_103848 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | breast cancer |
| ICD-0-3 | C50 |
| Methods | qPCR, Luciferase reporter assay, Western blot |
| Sample | BC tissues and cell lines(MCF-10A,MDA-MB-231, MDA-MB-468, MCF7 and MDA-MB-415) |
| Expression Pattern | up-regulated |
| Function Description | This study aimed to explore the biological role of lncRNA CASC9 in BC and to elucidate the molecular mechanisms involved. lncRNA CASC9 was found to be significantly upregulated in both BC tissues and cell lines. |
| Pubmed ID | 30816435 |
| Year | 2019 |
| Title | lncRNA CASC9 positively regulates CHK1 to promote breast cancer cell proliferation and survival through sponging the miR-195/497 cluster. |
External Links
| Links for CASC9 | GenBank HGNC NONCODE |
| Links for breast cancer | OMIM COSMIC |