Basic Information
| LncRNA/CircRNA Name | ZFAS1 |
| Synonyms | ZFAS1, C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1-AS1 |
| Region | GRCh38_20:49278178-49295738 |
| Ensemble | ENSG00000177410 |
| Refseq | NR_003604 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | nasopharyngeal cancer |
| ICD-0-3 | C11 |
| Methods | qPCR, Western blot, etc. |
| Sample | nasopharyngeal cancer tissues, cell lines (CNE-1, CNE-2, HNE-1, NP-69, HONE-1, SUNE-1) |
| Expression Pattern | up-regulated |
| Function Description | ZFAS1 was overexpressed in NPC and was significantly related to tumor size, lymph node metastasis and poor prognosis of NPC. ZFAS1 could promote NPC by activating Wnt/B-catenin pathway. |
| Pubmed ID | 29917194 |
| Year | 2018 |
| Title | Long non-coding RAN ZFAS1 promotes nasopharyngeal carcinoma through activation of Wnt/?-catenin pathway. |
External Links
| Links for ZFAS1 | GenBank HGNC NONCODE |
| Links for nasopharyngeal cancer | OMIM COSMIC |