Basic Information
| LncRNA/CircRNA Name | ZFAS1 |
| Synonyms | ZFAS1, C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1-AS1 |
| Region | GRCh38_20:49278178-49295738 |
| Ensemble | ENSG00000177410 |
| Refseq | NR_003604 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | non small cell lung cancer |
| ICD-0-3 | C34 |
| Methods | qPCR etc. |
| Sample | NSCLC tissues |
| Expression Pattern | up-regulated |
| Function Description | ZFAS1 was upregulated in NSCLC tissues and higher expression levels of ZFAS1 were found in more advanced tumor tissues. ZFAS1 expression levels were significantly associated with tumor differentiation grade, lymph node metastasis and TMN stage. Furthermore, we found that patients with higher ZFAS1 expression level are associated with a poorer overall survival. |
| Pubmed ID | 28051258 |
| Year | 2016 |
| Title | Overexpression of long-noncoding RNA ZFAS1 decreases survival in human NSCLC patients. |
External Links
| Links for ZFAS1 | GenBank HGNC NONCODE |
| Links for non small cell lung cancer | OMIM COSMIC |