Basic Information
| LncRNA/CircRNA Name | ZFAS1 |
| Synonyms | ZFAS1, C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1-AS1 |
| Region | GRCh38_20:49278178-49295738 |
| Ensemble | ENSG00000177410 |
| Refseq | NR_003604 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | qPCR etc. |
| Sample | cell lines (A2008, HeyA8, and HeyC2) |
| Expression Pattern | up-regulated |
| Function Description | In vitro experiment results showed that the ZFAS1 expression level was upregulated in A2008, HeyA8, and HeyC2 cell lines treated with cisplatin compared with the control group, which indicates that cisplatin could increase the ZFAS1 expression level in ovarian cancer cells. |
| Pubmed ID | 28154416 |
| Year | 2017 |
| Title | Long noncoding RNA expression signature to predict platinum-based chemotherapeutic sensitivity of ovarian cancer patients. |
External Links
| Links for ZFAS1 | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |