Basic Information
LncRNA/CircRNA Name | CASC9 |
Synonyms | NA |
Region | GRCh38_8:75223404-75324741 |
Ensemble | ENSG00000249395 |
Refseq | NR_103848 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | colorectal cancer |
ICD-0-3 | C19.9 |
Methods | qRT-PCR, Western blot |
Sample | CRC tissues,cell lines |
Expression Pattern | up-regulated |
Function Description | CASC9, an oncogenic lncRNA, was abnormally up-regulated in CRC tissues, and it could indirectly modulate the expression of ERBB2 via reducing the expression level of miR-193a-5p. |
Pubmed ID | 32110102 |
Year | 2020 |
Title | Long Non-Coding RNA Cancer Susceptibility 9 (CASC9) Up-Regulates the Expression of ERBB2 by Inhibiting miR-193a-5p in Colorectal Cancer |
External Links
Links for CASC9 | GenBank HGNC NONCODE |
Links for colorectal cancer | OMIM COSMIC |