Basic Information
| LncRNA/CircRNA Name | ZFAS1 |
| Synonyms | NA |
| Region | GRCh38_20:49278178-49295738 |
| Ensemble | ENSG00000177410 |
| Refseq | NR_003604 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | thyroid cancer |
| ICD-0-3 | C73.9 |
| Methods | qRT-PCR , in vitro knockdown etc. |
| Sample | thyroid cancer tissues and non-cancerous tissues ,cell lines(CAL62 and SW579) |
| Expression Pattern | up-regulated |
| Function Description | ZFAS1 was highly expressed in thyroid cancer compared to normal samples.Moreover,upregulation of ZFAS1 was positively correlated with clinicopathological features and poor prognosis in thyroid cancer.Knockdown of ZFAS1 suppressed cell proliferation and cell cycle in thyroid cancer cells.ZFAS1 was associated with translation, rRNA processing, intra-Golgi vesicle-mediated transport, ribosome, and ubiquitin-mediated proteolysis. |
| Pubmed ID | 31012438 |
| Year | 2019 |
| Title | Long Non-Coding RNA ZFAS1 as a Novel Potential Biomarker for Predicting the Prognosis of Thyroid Cancer |
External Links
| Links for ZFAS1 | GenBank HGNC NONCODE |
| Links for thyroid cancer | OMIM COSMIC |