Basic Information
| LncRNA/CircRNA Name | ZEB1-AS1 |
| Synonyms | NR_024284 |
| Region | GRCh38_10:31206278-31320447 |
| Ensemble | ENSG00000237036 |
| Refseq | NR_024284 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot etc. |
| Sample | cell lines (NCI-N87, SNU-1, AGS, MKN-45) |
| Expression Pattern | up-regulated |
| Function Description | ZEB1-AS1 regulated gastric cancer cells migration, invasion and EMT process.ZEB1-AS1 positively regulated ZEB1 expression in gastric cancer cells, and had a strongly positive correlation with ZEB1 expression in gastric cancer tissues.Rescued-function studies showed ZEB1 was critical for ZEB1-AS1 induced gastric cancer cells migration, invasion and EMT process. |
| Pubmed ID | 29113674 |
| Year | 2017 |
| Title | LncRNA ZEB1-AS1 predicts unfavorable prognosis in gastric cancer |
External Links
| Links for ZEB1-AS1 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |