Basic Information
| LncRNA/CircRNA Name | ZEB1-AS1 |
| Synonyms | NA |
| Region | GRCh38_10:31206278-31320447 |
| Ensemble | ENSG00000237036 |
| Refseq | NR_024284 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | RT-qPCR, in vitro knockdown etc. |
| Sample | U87MG glioblastoma cells |
| Expression Pattern | up-regulated |
| Function Description | The expression of LncZEB1-AS1 in Si group was significantly lower than that in the NC and blank groups.The apoptosis rate in the Si group was significantly higher than that in the NC and blank groups. Inhibition of LncRNA ZEB1-AS1 can inhibit the proliferation and invasion of glioma U87 cells and promote apoptosis. |
| Pubmed ID | 31186725 |
| Year | 2019 |
| Title | Effect of lncRNA ZEB1-AS1 on Proliferation, Invasion and Apoptosis of Glioma U87 Cells |
External Links
| Links for ZEB1-AS1 | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |