Basic Information
| LncRNA/CircRNA Name | XLOC_100055 |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | esophageal cancer |
| ICD-0-3 | C15 |
| Methods | RNA-seq, qPCR etc. |
| Sample | esophageal cancer tissues, cell lines (KYSE30, KYSE70, KYSE140, KYSE150, KYSE180, KYSE410, KYSE450, KYSE510, KYSE520, TE3, TE7, TE9) |
| Expression Pattern | down-regulated |
| Function Description | Loss of Lnc-22 (XLOC_100055) expression was found in KYSE30, KYSE70, KYSE140, KYSE150, KYSE410, KYSE450, KYSE520 and TE8 cells, while it was highly expressed in KYSE180, KYSE510, TE3 and TE7 cells, as well as in normal esophageal mucosa. The expression of Lnc-22 was reduced in 75% (9/12) esophageal cancer samples compared to adjacent tissue samples. |
| Pubmed ID | 27115166 |
| Year | 2016 |
| Title | Systematic study of novel lncRNAs in different gastrointestinal cancer cells. |
External Links
| Links for XLOC_100055 | GenBank HGNC NONCODE |
| Links for esophageal cancer | OMIM COSMIC |