Basic Information
| LncRNA/CircRNA Name | XLOC_010235 |
| Synonyms | lnc-NCOR2-1, XLOC_010235, linc-CCDC92-2 |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | gastric cancer |
| ICD-0-3 | C16 |
| Methods | qPCR, Western blot etc. |
| Sample | cell lines (AGS, BGC-823, BGC-803, SGC-7901, HGC-27, MKN-1) |
| Expression Pattern | up-regulated |
| Function Description | Ectopic expression of XLOC facilitate cell viability, migration and invasion, leading to the acceleration of metastasis, while depletion of XLOC expression hindered cell migration and invasion. |
| Pubmed ID | 28550287 |
| Year | 2017 |
| Title | Up-regulation of long non-coding RNA XLOC_010235 regulates epithelial-to-mesenchymal transition to promote metastasis by associating with Snail1 in gastric cancer |
External Links
| Links for XLOC_010235 | GenBank HGNC NONCODE |
| Links for gastric cancer | OMIM COSMIC |