Basic Information
| LncRNA/CircRNA Name | 91H |
| Synonyms | NA |
| Region | NA |
| Ensemble | NA |
| Refseq | NA |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR, Cell transfection, Flow cytometry assay, Cell proliferation assay etc. |
| Sample | osteosarcoma tissues, cell lines (SAOS-2, U2OS, MG63, HOS, hFOB) |
| Expression Pattern | up-regulated |
| Function Description | Herein, we confirmed that 91H expression was notably increased in osteosarcoma patients and cell lines compared to healthy controls and normal human bone cell lines. High expression of 91H was significantly correlated with advanced clinical stage, chemotherapy after surgery, and tumor size >5 cm. Additionally, the knockdown of 91H expression inhibited osteosarcoma cells' proliferation and promoted their apoptosis in vitro. |
| Pubmed ID | 27555785 |
| Year | 2016 |
| Title | Clinical implication of long noncoding RNA 91H expression profile in osteosarcoma patients. |
External Links
| Links for 91H | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |