Basic Information
| LncRNA/CircRNA Name | XIST |
| Synonyms | XIST, DXS1089, DXS399E, LINC00001, NCRNA00001, SXI1, swd66 |
| Region | GRCh38_X:73820651-73852753 |
| Ensemble | ENSG00000229807 |
| Refseq | NR_001564 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | ovarian cancer |
| ICD-0-3 | C56.9 |
| Methods | Microarray, qPCR etc. |
| Sample | ovarian cancer tissues, cell lines (NOSE, EOC etc.) |
| Expression Pattern | down-regulated |
| Function Description | A series of malignant ovarian tumor samples were investigated for XIST expression. XIST expression was detectable by RT-PCR in the majority of EOC samples tested but was expressed at very low levels in four of 15 (27%) EOC samples, TOV921G, TOV1118D, TOV837, and TOV1054G. |
| Pubmed ID | 17143508 |
| Year | 2007 |
| Title | Global analysis of chromosome X gene expression in primary cultures of normal ovarian surface epithelial cells and epithelial ovarian cancer cell lines. |
External Links
| Links for XIST | GenBank HGNC NONCODE |
| Links for ovarian cancer | OMIM COSMIC |