Basic Information
| LncRNA/CircRNA Name | CASC2 |
| Synonyms | CASC2, C10orf5 |
| Region | GRCh38_10:118046279-118210153 |
| Ensemble | ENSG00000177640 |
| Refseq | NR_026939 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | thyroid cancer |
| ICD-0-3 | C73.9 |
| Methods | qPCR |
| Sample | Human thyroid epithelium cell lines (BCPAP, FTC133, 8505C,HTH-83), renal cell carcinoma tissues. |
| Expression Pattern | down-regulated |
| Function Description | Our findings showed that CASC2 may be a potential prognostic marker and therapeutic target.Kaplan-Meier survival analysis and multivariate analysis showed that CASC2 expression may be an independent prognostic factor in human thyroid carcinoma. |
| Pubmed ID | 28654795 |
| Year | 2017 |
| Title | Low expression of long noncoding RNA CASC2 indicates a poor prognosis and promotes tumorigenesis in thyroid carcinoma. |
External Links
| Links for CASC2 | GenBank HGNC NONCODE |
| Links for thyroid cancer | OMIM COSMIC |