Basic Information
LncRNA/CircRNA Name | XIST |
Synonyms | NA |
Region | GRCh38_X:73820651-73852753 |
Ensemble | ENSG00000229807 |
Refseq | NR_001564 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | apoptosis | Drug | ||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | cervical cancer |
ICD-0-3 | C53 |
Methods | qPCR, Luciferase reporter assay, Western blot |
Sample | cervical cancer tissues, cell lines (Hela and C33A) |
Expression Pattern | up-regulated |
Function Description | Up-regulated lncRNA XIST contributes to progression of cervical cancer via regulating miR-140-5p and ORC1. |
Pubmed ID | 30858762 |
Year | 2019 |
Title | Up-regulated lncRNA XIST contributes to progression of cervical cancer via regulating miR-140-5p and ORC1. |
External Links
Links for XIST | GenBank HGNC NONCODE |
Links for cervical cancer | OMIM COSMIC |