Basic Information
LncRNA/CircRNA Name | XIST |
Synonyms | NA |
Region | GRCh38_X:73820651-73852753 |
Ensemble | ENSG00000229807 |
Refseq | NR_001564 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | colorectal cancer |
ICD-0-3 | C19.9 |
Methods | qPCR, Luciferase reporter assay, Western blot |
Sample | colorectal cancer tissues,cell lines |
Expression Pattern | up-regulated |
Function Description | Our results demonstrated that XIST and ROR1 expressions were dramatically up-regulated, yet miR-30a-5p expression was down-regulated within colorectal cancer tissues |
Pubmed ID | 30907503 |
Year | 2019 |
Title | Atractylenolide II reverses the influence of lncRNA XIST/miR-30a-5p/ROR1 axis on chemo-resistance of colorectal cancer cells. |
External Links
Links for XIST | GenBank HGNC NONCODE |
Links for colorectal cancer | OMIM COSMIC |