Basic Information
| LncRNA/CircRNA Name | XIST |
| Synonyms | NA |
| Region | GRCh38_X:73820651-73852753 |
| Ensemble | ENSG00000229807 |
| Refseq | NR_001564 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | glioma |
| ICD-0-3 | NA |
| Methods | qPCR, Western blot |
| Sample | glioma cell lines (U251, LN229, T98G, LN18, and A172) |
| Expression Pattern | down-regulated |
| Function Description | knocking down LncRNA-XIST induced the inhibition of the progression of glioma by way of triggering ROS production in a miR-137/SLC1A5 axis-dependent manner. |
| Pubmed ID | 32036410 |
| Year | 2020 |
| Title | Knock-down of LncRNA-XIST inducedglioma cell death and inhibited tumorigenesis by regulating miR-137/SLC1A5 axis-mediated ROS production |
External Links
| Links for XIST | GenBank HGNC NONCODE |
| Links for glioma | OMIM COSMIC |