Basic Information
| LncRNA/CircRNA Name | WWOX-AS1 |
| Synonyms | WWOX-AS1 |
| Region | GRCh38_16: 78237362-78241218 |
| Ensemble | ENSG00000260969 |
| Refseq | XR_429776 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | osteosarcoma |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | osteosarcoma tissues, cell lines (SAOS2, MG63 and U2OS) |
| Expression Pattern | up-regulated |
| Function Description | Furthermore, the results of the knockdown and overexpression functional experiments suggested that WWOX-AS1 overexpression inhibited the proliferation, migration and invasion of MG63 cells, and knockdown of WWOX-AS1 enhanced the proliferation, migration and invasion of MG63 cells in SAOS2 cells. |
| Pubmed ID | 29845204 |
| Year | 2018 |
| Title | LncRNA WWOX-AS1 inhibits the proliferation, migration and invasion of osteosarcoma cells |
External Links
| Links for WWOX-AS1 | GenBank HGNC NONCODE |
| Links for osteosarcoma | OMIM COSMIC |