Basic Information
| LncRNA/CircRNA Name | WT1-AS |
| Synonyms | WT1-AS, WIT-1, WIT1, WT1-AS1, WT1AS |
| Region | GRCh38_11:32435518-32458769 |
| Ensemble | ENSG00000183242 |
| Refseq | NR_023920 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | acute myeloid leukemia |
| ICD-0-3 | NA |
| Methods | qPCR etc. |
| Sample | Bone marrow |
| Expression Pattern | up-regulated |
| Function Description | AML arose by abnormal splicing events at different positions compared with the AS1/8 splice sites, with almost all of the splice junctions lacking the normal 59GT and 39AG intron splice motifs. |
| Pubmed ID | 17940140 |
| Year | 2007 |
| Title | Alternately spliced WT1 antisense transcripts interact with WT1 sense RNA and show epigenetic and splicing defects in cancer. |
External Links
| Links for WT1-AS | GenBank HGNC NONCODE |
| Links for acute myeloid leukemia | OMIM COSMIC |