Basic Information
| LncRNA/CircRNA Name | WT1AS |
| Synonyms | WT1-AS, WIT-1, WIT1, WT1-AS1, WT1AS |
| Region | GRCh38_11:32435518-32458769 |
| Ensemble | ENSG00000183242 |
| Refseq | NR_023920 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colon cancer |
| ICD-0-3 | C18 |
| Methods | Microarray, qPCR, RNA pull-down assay etc. |
| Sample | cell line (HCT-117) |
| Expression Pattern | down-regulated |
| Function Description | Quantitative RT-PCR analyses confirmed transcriptional silencing in HCT-116 cells and demethylation-associated reactivation in DKO cells for seven (70%) of the lncRNAs: TP53TG1, NCRNA00028, LOC157627, MIR155HG, WT1AS, C20orf200, and MYCNOS. |
| Pubmed ID | 27821766 |
| Year | 2016 |
| Title | Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer. |
External Links
| Links for WT1AS | GenBank HGNC NONCODE |
| Links for colon cancer | OMIM COSMIC |