Basic Information
| LncRNA/CircRNA Name | WDFY3-AS2 |
| Synonyms | NA |
| Region | GRCh38_4:84965682-85011277 |
| Ensemble | ENSG00000180769 |
| Refseq | NR_015359 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | apoptosis | Drug | ||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | lung adenocarcinoma |
| ICD-0-3 | C34 |
| Methods | qPCR, Western blot, Luciferase reporter assay, RIP etc |
| Sample | LUAD tissue samples and adjacent nontumor tissues, cell lines (SPCA-1, PC9, A549, H1975, HBE) |
| Expression Pattern | up-regulated |
| Function Description | WDFY3-AS2 is abnormally overexpressed and silencing WDFY3-AS2 inhibits cell proliferation, migration, and invasion, whereas accelerates cell apoptosis in LUAD. |
| Pubmed ID | 32275336 |
| Year | 2020 |
| Title | USF1-induced Overexpression of Long Noncoding RNA WDFY3-AS2 Promotes Lung Adenocarcinoma Progression via Targeting miR-491-5p/ZNF703 Axis |
External Links
| Links for WDFY3-AS2 | GenBank HGNC NONCODE |
| Links for lung adenocarcinoma | OMIM COSMIC |