Basic Information
| LncRNA/CircRNA Name | UXT-AS1 |
| Synonyms | NA |
| Region | GRCh38_X:47658833-47660377 |
| Ensemble | ENSG00000267064 |
| Refseq | NR_028119 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | colorectal cancer |
| ICD-0-3 | C19.9 |
| Methods | qPCR, Western blot |
| Sample | colorectal cancer tissues, cell lines (HT29, HCT116 and SW480) |
| Expression Pattern | up-regulated |
| Function Description | UXT-AS1 was found to be significantly upregulated in colorectal cancer (CRC) and high expression levels of UXT-AS1 were significantly associated with poor prognosis in CRC patients. |
| Pubmed ID | 28401004 |
| Year | 2017 |
| Title | UXT-AS1-induced alternative splicing of UXT is associated with tumor progression in colorectal cancer |
External Links
| Links for UXT-AS1 | GenBank HGNC NONCODE |
| Links for colorectal cancer | OMIM COSMIC |