Basic Information
| LncRNA/CircRNA Name | UCA1 |
| Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
| Region | GRCh38_19:15828206-15836326 |
| Ensemble | ENSG00000214049 |
| Refseq | NR_015379 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | bladder cancer |
| ICD-0-3 | C67 |
| Methods | Microarray, RT-qPCR, Western blot |
| Sample | bladder cancer cell line (UM-UC-2) |
| Expression Pattern | up-regulated |
| Function Description | the lncRNA UCA1a expression level was significantly increased when compared to that of pCDNA3.1(+) transfected cells. Cell proliferation activity was significantly increased following overexpression of lncRNA UCA1a increasing over culture time. |
| Pubmed ID | 28815726 |
| Year | 2017 |
| Title | Differential expression profile analysis of lncRNA UCA1a regulated mRNAs in bladder cancer. |
External Links
| Links for UCA1 | GenBank HGNC NONCODE |
| Links for bladder cancer | OMIM COSMIC |