Basic Information
LncRNA/CircRNA Name | UCA1 |
Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
Region | GRCh38_19:15828206-15836326 |
Ensemble | ENSG00000214049 |
Refseq | NR_015379 |
Classification Information
Regulatory Mechanism | Biological Function | Clinical Application | |||
---|---|---|---|---|---|
TF | Immune | Survival | |||
Enhancer | Apoptosis | Drug | |||
Variant | Cell Growth | Circulating | |||
MiRNA | EMT | Metastasis | |||
Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
Cancer Name | hepatocellular carcinoma |
ICD-0-3 | C22.0 |
Methods | qPCR, Western blot etc. |
Sample | cell line (HuH7, HuH7.6) |
Expression Pattern | up-regulated |
Function Description | Two of these CSRs (PVT1 and UCA2) play relevant roles in tumorigene-sis, providing a novel link between HCV infection and developmentof liver tumors. |
Pubmed ID | 27283940 |
Year | 2016 |
Title | Long noncoding RNA EGOT negatively affects the antiviral response and favors HCV replication |
External Links
Links for UCA1 | GenBank HGNC NONCODE |
Links for hepatocellular carcinoma | OMIM COSMIC |