Basic Information
| LncRNA/CircRNA Name | UCA1 |
| Synonyms | UCA1, CUDR, LINC00178, NCRNA00178, UCAT1, onco-lncRNA-36 |
| Region | GRCh38_19:15828206-15836326 |
| Ensemble | ENSG00000214049 |
| Refseq | NR_015379 |
Classification Information
| Regulatory Mechanism | Biological Function | Clinical Application | |||
|---|---|---|---|---|---|
| TF | Immune | Survival | |||
| Enhancer | Apoptosis | Drug | |||
| Variant | Cell Growth | Circulating | |||
| MiRNA | EMT | Metastasis | |||
| Methylation | Coding Ability | Recurrence |
Cancer&Entry Information
| Cancer Name | hepatocellular carcinoma |
| ICD-0-3 | C22.0 |
| Methods | qPCR |
| Sample | hepatocellular carcinoma tissues |
| Expression Pattern | up-regulated |
| Function Description | High expression of serum UCA1 was significantly associated with a high tumor grade, large tumor size,positive vascular invasion, and advanced TNM stage.a high serum UCA1 level was an independent unfavorable prognostic factor for HCC. High levels of UCA1 in HCC tumor tissues are closely related to large tumor size, vascular invasion,advanced TNM stage, and poor postoperative survival. |
| Pubmed ID | 28856933 |
| Year | 2017 |
| Title | Serum long noncoding RNA urothelial carcinoma-associated 1: A novel biomarker for diagnosis and prognosis of hepatocellular carcinoma. |
External Links
| Links for UCA1 | GenBank HGNC NONCODE |
| Links for hepatocellular carcinoma | OMIM COSMIC |